Mouse Leukemia Inhibitory Factor (LIF) is member of the IL-6 family and is made by a variety of tissues. LIF signals through receptors gp190 (LIFR) and gp130 to activate STAT3 which ultimately promotes mouse embryonic stem cell self-renewal and pluripotentcy of long term cultures. This activity is similar to that attributed to FGF-basic (FGF-2) for human embryonic stem cells.
This product is produced using Animal Free raw components and processes, in a non-mammalian system.
Ships ambient. Store frozen at -20 to -10C.
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