mGM-CSF is produced in response to a number of inflammatory mediators by mesenchymalcells present in the hemopoietic environment and at peripheral sites of inflammation.It is able to stimulate the production of neutrophilic granulocytes, macrophages and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells.GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.GM-CSF receptors show significant homologies with other receptors for hematopoietic growth factors, including IL2-beta, IL-3, IL-6, IL-7, EPO and the prolactin receptors. This carrier-free product is a recombinant protein expressed in E. coli.
Ships ambient. Store frozen -20 to -10C.
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